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📊 Combination Therapy - Antihistamine + Steroid

Research examining synergistic effects of antihistamine-steroid combinations in managing immediate and delayed allergic responses.

Articles

Combination Therapy - Antihistamine + Steroid

Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis

Paul H Ratner, Frank Hampel, Julius Van Bavel

Annals of Allergy, Asthma & Immunology • 2008

This 2-week, multicenter, randomized, double-blind clinical trial assessed the efficacy of combining intranasal azelastine (antihistamine) with fluticasone propionate (corticosteroid) for patients with moderate to severe seasonal allergic rhinitis (SAR) during the Texas mountain cedar season. The goal was to determine if concurrent use of these agents produced greater symptom relief than either agent alone.