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/ 📊 Combination Therapy - Anti-Discharge + Decongestant

📊 Combination Therapy - Anti-Discharge + Decongestant

Clinical evidence for triple-combination therapy addressing multiple allergic rhinitis symptoms through synergistic mechanisms.

Articles

Combination Therapy - Anti-Discharge + Decongestant

Efficacy and safety of topical combinations of ipratropium and xylometazoline for the treatment of symptoms of runny nose and nasal congestion associated with acute upper respiratory tract infection

Ronald Eccles, Anette Pedersen, Dan Regberg

American Journal of Rhinology & Allergy • 2007

This randomized, double-blind, placebo-controlled study assessed the safety and effectiveness of a nasal spray combining ipratropium bromide (an anticholinergic agent) and xylometazoline (a decongestant) in treating rhinorrhea and nasal congestion associated with the common cold. Over a 7-day treatment period, patients scored symptoms and tracked tissue use, with five different treatment arms studied.