The Research

/ 📊 Combination Therapy - Anti-Discharge + Anti-Inflammatory Corticosteroid

📊 Combination Therapy - Anti-Discharge + Anti-Inflammatory Corticosteroid

Research on combined anti-discharge and corticosteroid treatments for comprehensive management of rhinorrhea and inflammation.

Articles

Combination Therapy - Anti-Discharge + Anti-Inflammatory Corticosteroid

Ipratropium bromide nasal spray 0.03% and beclomethasone nasal spray alone and in combination for the treatment of rhinorrhea in perennial rhinitis

R Dockhorn, D Aaronson, E Bronsky, P Chervinsky, R Cohen

Annals of Allergy, Asthma & Immunology • 1999

This randomized, double-blind, placebo-controlled study investigated the efficacy and safety of combining ipratropium bromide nasal spray 0.03% (an anticholinergic agent) with beclomethasone dipropionate nasal spray (a corticosteroid) in patients with perennial rhinitis. A total of 533 patients received either the combination therapy, ipratropium alone, beclomethasone alone, or placebo for a period of four weeks. The study measured both physician- and patient-assessed outcomes including severity and duration of rhinorrhea, congestion, and sneezing.