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Scientific Index

The Research

/ 📊 Combination Therapy

📊 Combination Therapy

Studies evaluating multi-drug formulations that target multiple pathways of allergic response for enhanced therapeutic outcomes.

Articles

Combination Therapy
Combined medical therapy in the treatment of allergic rhinitis: Systematic review and meta-analyses

Wirach Chitsuthipakorn, Minh P. Hoang

International Forum of Allergy & Rhinology • 2022

This systematic review and meta-analysis assessed the effectiveness of various combination therapies compared to monotherapies in treating allergic rhinitis (AR). The study analyzed data from 53 randomized controlled trials, focusing on combinations such as antihistamines (ATH) with decongestants, leukotriene receptor antagonists (LTRA), or saline irrigation, and intranasal corticosteroids (INCS) combined with intranasal antihistamines, LTRA, decongestants, or saline irrigation. 

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Combination Therapy
The Study of a Novel Triple Spray Combination of Corticosteroid, Antihistamine and Decongestant Delivered in a Single Spray

Reimus Valencia, Phuong Daniels

Journal of Allergy and Clinical Immunology • 2021

This study evaluated a novel triple spray composed of triamcinolone (a corticosteroid), azelastine (an antihistamine), and oxymetazoline (a decongestant) delivered in a single formulation. The goal was to determine whether this combination offered superior symptom relief for allergic rhinitis (AR) compared to the use of a single-agent nasal spray.

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