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/ Rescue Rebound Program / Will Allermi cause rebound congestion since it contains oxymetazoline?

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Will Allermi cause rebound congestion since it contains oxymetazoline?

Updated Tue, Mar 24, 2026

The short answer is no. This is because Allermi contains a prescription-only micro-dose of oxymetazoline that is a tiny fraction of the dosage of what is in over-the-counter oxymetazoline products such as Afrin™ and it is paired with an anti-inflammatory ingredient.

In a tiny micro-dose as in Allermi, oxymetazoline gently relieves congestion and improves the efficacy & reach of the other ingredients in your formula. We then combine that micro-dosage with an anti-inflammatory corticosteroid. Studies suggest that when the dosage is reduced and combined with anti-inflammatory in the same formula, the risk of rebound is essentially eliminated and has been shown to reverse existing rebound congestion from previous high-dose decongestant spray use.